영남대학교

CV(PDF)

이메일
Reviews & Commentaries
Roles of Indole as an Interspecies and Interkingdom Signaling Molecule
펼치기 Authors and Affiliations
Abstract

A variety of bacteria, and some plants, produce large quantities of indole, and thus, indole and its derivatives are widespread in prokaryotic and eukaryotic communities. Recently, indole was shown to be an intercellular, interspecies, and interkingdom signaling molecule.

Indole and its derivatives can suppress the bacterial pathogenesis of several antibiotic-resistant pathogens by inhibiting quorum sensing and virulence factor production.

Insects sense indole, which controls their behavior. Furthermore, indole controls plant defense systems and growth, and modulates oxidative stress, intestinal inflammation, and hormone secretion in animals. Emerging data suggest that indoles may influence human diseases, such as inflammatory, neurological, and metabolic diseases.

Keywords : antivirulence approach; bacteria-host interaction; indole and its derivatives; interkingdom signaling molecule

주소복사
논문정보   
- 형식: Review Paper
- 게재일: 2015년 11월 (BRIC 등록일 2020-03-31)
- 연구진: 국내(교신)+국외 연구진태극기
- 분야: Microbiology
- 피인용횟수: 120회 이상 인용된 논문
댓글 (0)
웨비나 참석자 모집중...
HOME   |   이용약관   |   개인정보처리방침
© BRIC