Prasad Subramaniam¹, Seung Jae Lee^1,2, Shreyas Shah¹, Sahishnu Patel¹, Valentin Starovoytov³, Ki-Bum Lee^1,4,*

¹Department of Chemistry and Chemical Biology, Institute for Advanced Materials, Devices and Nanotechnology (IAMDN), Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
²Center for Nano-Bio Fusion Research, Korea Research Institute of Chemical Technology, Daejeon 305-600, Korea
³Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
⁴School of Medicine, Kyung Hee University, Seoul, South Korea

^*Corresponding author : Ki-Bum Lee
Department of Chemistry and Chemical Biology, Institute for Advanced Materials, Devices and Nanotechnology (IAMDN), Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA.

The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS₂ (ZAIS) quantum dots for cellular imaging and siRNA delivery.

Keywords:non-toxic quantum dots;sonochemistry;siRNA delivery;stem cell imaging;nanomaterial libraries