Rutgers, The State University of New Jersey


댓글 1
Selective Inhibition of Human Brain Tumor Cells through Multifunctional Quantum-Dot-Based siRNA Delivery
펼치기 Authors and Affiliations

More than one job: Quantum dots (QDs) conjugated with thiol-modified small interfering RNA (siRNA) were functionalized with thiol-modified RGD and HIV-Tat peptides. These multifunctional QDs were used for the targeted delivery and tracking of siRNA molecules for the knockdown of the EGFRvIII gene, which led to the down-regulation of the PI3K-Akt signaling pathway and the apoptosis of malignant brain cancer cells.

antitumor agents, gene knockdown, nanoparticles, nonviral siRNA delivery, target-specific delivery

- 형식: Research article
- 게재일: 2009년 12월 (BRIC 등록일 2009-12-11)
- 연구진: 국외연구진
댓글 (1)
지냐  |  2009.12.16 12:18     
앗 종진형!! 축하드려요!!
ㅋㅋㅋㅋ 고생하시더니.. 이제 졸업하셔야겠네!
저는 넬슨에 있는 이 모군.
웨비나 참석자 모집중...
HOME   |   이용약관   |   개인정보처리방침